Description

Phosphonic Acid, (1-Carboxyamino-1-Methylethyl)- (5Ci) is a specialized organophosphorus compound featuring a unique carboxyamino functional group. This structural motif makes it a valuable intermediate for synthesizing complex molecules, particularly in the development of novel pharmaceuticals and advanced agrochemicals. It is essential for research chemists and process development teams in the fine chemical and life science industries seeking to introduce phosphonate or phosphonic acid moieties into target structures. The compound's reactivity profile offers a strategic pathway for creating molecules with tailored biological activity or material properties.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting bone disorders, cardiovascular diseases, or as protease inhibitors.
• Agrochemical Research: Used in developing new herbicides, plant growth regulators, or fungicides where the phosphonic acid group can mimic natural phosphates or act as a stable bioisostere.
• Ligand Synthesis: Acts as a precursor for chelating agents and ligands in catalysis, metal extraction, or in the preparation of metal-organic frameworks (MOFs).
• Surface Modification Agent: Can be utilized to functionalize surfaces (e.g., metals, oxides) to impart corrosion resistance, improve adhesion, or create specific surface chemistries.
• Flame Retardant Synergist: Investigated as a component in flame-retardant formulations for polymers and textiles, where phosphorus-containing compounds promote char formation.
• Bioconjugation Chemistry: Employed in bioconjugation strategies for attaching probes, drugs, or other molecules to biomolecules like proteins or peptides.

Basic Information

Item	Details
Product Name	Phosphonic Acid, (1-Carboxyamino-1-Methylethyl)- (5Ci)
CAS No.	872813-45-1
Molecular Formula	C4H10NO5P
Molecular Weight	183.10 g/mol
Synonyms	1-Amino-2-methyl-1-phosphonopropionic acid; (1-Carboxyamino-1-methylethyl)phosphonic acid; 2-Amino-2-methyl-3-phosphonopropanoic acid; 2-Amino-2-methyl-3-phosphonopropionic acid; 3-Phosphono-DL-isoserine; α-Amino-α-methyl-β-phosphonopropionic acid; AMPPA; NSC 339586
EINECS	Contact for details

Quality Control

Every batch of Phosphonic Acid, (1-Carboxyamino-1-Methylethyl)- (5Ci) is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment, ensuring full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.