Description

tert-Butyl (4-Bromo-6-Methoxyquinolin-3-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its specific quinoline-based molecular structure. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, where precise chemical functionality and reliable purity are paramount for successful outcomes.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug molecules, especially in oncology and antiviral therapeutic areas.
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses to introduce the functionalized quinoline moiety into larger molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Chemistry Development: Integral for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API production.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	tert-Butyl (4-Bromo-6-Methoxyquinolin-3-Yl)Carbamate
CAS No.	872714-59-5
Molecular Formula	C₁₅H₁₇BrN₂O₃
Molecular Weight	353.21 g/mol
Synonyms	Boc-4-Bromo-6-methoxy-3-aminoquinoline; 3-[(tert-Butoxycarbonyl)amino]-4-bromo-6-methoxyquinoline; 4-Bromo-6-methoxyquinolin-3-yl-carbamic acid tert-butyl ester; tert-Butyl N-(4-bromo-6-methoxy-3-quinolyl)carbamate; 4-Bromo-6-methoxy-3-quinolinamine, N-BOC-protected; BOC-4-Br-6-MeO-3-AQ; (4-Bromo-6-methoxy-quinolin-3-yl)-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Bromo-6-Methoxyquinolin-3-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.