Description

4(1)-Quinolone, 3-Chloro-6-Methyl-1-p-Tolylsulfonyl- (2Ci) is a high-purity, functionalized quinolone derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific chloromethyl and sulfonyl functionalities into heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinolone-based antibiotics, kinase inhibitors, and other therapeutic agents.
• Agrochemical Research: Used in developing new crop protection agents, including fungicides and herbicides, leveraging the quinolone core structure.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials and specialty polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for biological target identification.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and catalysis research at universities and CROs.

Basic Information

Product Name	4(1)-Quinolone, 3-Chloro-6-Methyl-1-p-Tolylsulfonyl- (2Ci)
CAS No.	872282-94-5
Molecular Formula	C17H14ClNO3S
Molecular Weight	347.81 g/mol
Synonyms	3-Chloro-6-methyl-1-(4-methylphenyl)sulfonyl-1H-quinolin-4-one; 3-Chloro-6-methyl-1-tosylquinolin-4(1H)-one; 1-Tosyl-3-chloro-6-methyl-4-quinolone; 3-Chloro-6-methyl-1-(p-tolylsulfonyl)-4(1H)-quinolone; 872282-94-5; 3-Chloro-6-methyl-1-(4-methylbenzenesulfonyl)quinolin-4(1H)-one
EINECS	Contact for details

Quality Control

Our 4(1)-Quinolone, 3-Chloro-6-Methyl-1-p-Tolylsulfonyl- (2Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.