Description

1-Propanone, 1-(2-Chloro-3-Methyloxiranyl)-2-Methyl- (9Ci) is a specialized oxirane derivative with a chloromethyl ketone functional group, making it a valuable and versatile chiral building block in advanced organic synthesis. This compound matters for its ability to introduce complex, functionalized epoxide motifs into target molecules, enabling the construction of intricate chemical architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in anti-infective and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and insecticides, where its epoxide ring can be selectively opened to create complex bioactive molecules.
• Fine Chemical Production: Serves as a critical building block for synthesizing specialty chemicals, flavors, fragrances, and performance materials requiring specific stereochemistry.
• Academic & Industrial R&D: Employed in methodological chemistry research for studying epoxide ring-opening reactions, asymmetric synthesis, and the development of new catalytic processes.
• Material Science Precursor: Potential use in the synthesis of monomers or cross-linking agents for specialized polymers and resins with tailored properties.

Basic Information

Product Name	1-Propanone, 1-(2-Chloro-3-Methyloxiranyl)-2-Methyl- (9Ci)
CAS No.	872129-92-5
Molecular Formula	C7H11ClO2
Molecular Weight	162.61 g/mol
Synonyms	2-Methyl-1-(2-chloro-3-methyloxiran-2-yl)propan-1-one; 1-(2-Chloro-3-methyloxiranyl)-2-methyl-1-propanone; 2-Chloro-3-methyl-2-(2-methylpropanoyl)oxirane; (2-Chloro-3-methyloxiran-2-yl)(isopropyl)methanone; α-Chloro-β-methylglycidyl isopropyl ketone; Glycidyl isopropyl ketone, 2-chloro-3-methyl-; Epoxide intermediate 872129-92-5
EINECS	Contact for details

Quality Control

Our 1-Propanone, 1-(2-Chloro-3-Methyloxiranyl)-2-Methyl- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. The product undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C/59-77°F). Keep away from strong acids, bases, and oxidizing agents. Due to the presence of an epoxide and ketone functional group, it should be handled and stored with appropriate chemical safety precautions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.