Description

1-Bromo-4-Cyclobutylmethoxybenzene is a high-purity organic intermediate featuring a brominated aromatic ring linked to a cyclobutylmethoxy substituent. This specific molecular architecture makes it a valuable building block for synthesizing more complex chemical entities, particularly in advanced pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry and agrochemical innovation.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or as kinase inhibitors.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced herbicides, fungicides, or plant growth regulators with tailored biological activity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis or as a core structure in organocatalysts.
• Material Science Research: Acts as a monomer or functionalization agent in the synthesis of advanced polymers, liquid crystals, or organic electronic materials.
• Cross-Coupling Reactions: The bromoaryl group makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	1-Bromo-4-Cyclobutylmethoxybenzene
CAS No.	871829-46-8
Molecular Formula	C11H13BrO
Molecular Weight	241.13 g/mol
Synonyms	4-Bromophenyl cyclobutyl methyl ether; 1-Bromo-4-(cyclobutylmethoxy)benzene; Benzene, 1-bromo-4-(cyclobutylmethoxy)-; p-Bromophenyl cyclobutylmethyl ether; Cyclobutylmethyl 4-bromophenyl ether; (4-Bromophenoxy)methylcyclobutane
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Cyclobutylmethoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.