Description

4(3H)-Quinazolinone, 7-Amino-3-(4-Chlorophenyl)-8-Methoxy-2-(1-Methylethyl)- is a high-purity, functionalized quinazolinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating targeted libraries and scaling up lead compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential kinase inhibitors, anticancer agents, and other therapeutic small molecules.
• Agrochemical Research: Building block for developing new herbicides, fungicides, or plant growth regulators with novel modes of action.
• Chemical Biology Probe Development: Used to create tool compounds for studying enzyme function and cellular signaling pathways.
• Material Science Research: Potential monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Academic & Contract Research: Serves as a starting material for methodological studies and novel heterocyclic chemistry in university and CRO laboratories.

Basic Information

Product Name	4(3H)-Quinazolinone, 7-Amino-3-(4-Chlorophenyl)-8-Methoxy-2-(1-Methylethyl)-
CAS No.	871814-54-9
Molecular Formula	C18H18ClN3O2
Molecular Weight	343.81 g/mol
Synonyms	7-Amino-3-(4-chlorophenyl)-8-methoxy-2-isopropylquinazolin-4(3H)-one; 7-Amino-3-(4-chlorophenyl)-8-methoxy-2-(1-methylethyl)-4(3H)-quinazolinone; 2-Isopropyl-7-amino-3-(4-chlorophenyl)-8-methoxy-4(3H)-quinazolinone; 871814-54-9; 4(3H)-Quinazolinone, 7-amino-3-(4-chlorophenyl)-8-methoxy-2-(1-methylethyl)-; 3-(4-Chlorophenyl)-7-amino-8-methoxy-2-isopropyl-3,4-dihydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Every batch of our 4(3H)-Quinazolinone derivative is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our quality commitment ensures the material is suitable for demanding GMP-grade pharmaceutical intermediate applications and rigorous research programs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.