Description

4(3H)-Quinazolinone, 7-Amino-3-(4-Chlorophenyl)-8-Hydroxy-2-(1-Methylethyl)- is a high-purity, synthetically derived quinazolinone derivative, serving as a critical advanced pharmaceutical intermediate. Its molecular structure, featuring a chlorophenyl substituent and amino-hydroxy functionality, makes it a valuable scaffold for medicinal chemistry research and development. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Intermediate in the research and synthesis of novel herbicides, fungicides, or insecticides.
• Chemical Biology Probe: Used in biochemical assays to study enzyme inhibition or protein-ligand interactions.
• Organic Synthesis: Versatile precursor for further functionalization and the construction of complex heterocyclic systems.

Basic Information

Product Name	4(3H)-Quinazolinone, 7-Amino-3-(4-Chlorophenyl)-8-Hydroxy-2-(1-Methylethyl)-
CAS No.	871814-50-5
Molecular Formula	C₁₇H₁₆ClN₃O₂
Molecular Weight	329.78 g/mol
Synonyms	7-Amino-3-(4-chlorophenyl)-8-hydroxy-2-isopropylquinazolin-4(3H)-one; 7-Amino-3-(4-chlorophenyl)-8-hydroxy-2-(1-methylethyl)-4(3H)-quinazolinone; 2-Isopropyl-7-amino-8-hydroxy-3-(p-chlorophenyl)-4(3H)-quinazolinone; 3-(4-Chlorophenyl)-7-amino-8-hydroxy-2-isopropyl-4(3H)-quinazolinone; AQHIC; CAS 871814-50-5
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliable performance in your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.