Description

Benzonitrile, 4-[8-Ethoxy-7-Hydroxy-2-(1-Methylethyl)-4-Oxo-3(4H)-Quinazolinyl]- is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 871814-30-1. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new drug candidates and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazolinone-based drug candidates.
• API Development: Used in research and development for potential therapeutics in oncology and other disease areas.
• Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds in medicinal chemistry.
• Biochemical Research: Employed as a reference standard or reagent in pharmacological and biochemical studies.
• Fine Chemical Production: Integral to the manufacture of high-purity, specialty chemicals for advanced applications.

Basic Information

Product Name	Benzonitrile, 4-[8-Ethoxy-7-Hydroxy-2-(1-Methylethyl)-4-Oxo-3(4H)-Quinazolinyl]-
CAS No.	871814-30-1
Molecular Formula	C20H19N3O4
Molecular Weight	365.38 g/mol
Synonyms	4-(8-Ethoxy-7-hydroxy-2-isopropyl-4-oxo-3,4-dihydroquinazolin-3-yl)benzonitrile; 3-(4-Cyanophenyl)-8-ethoxy-7-hydroxy-2-isopropyl-3,4-dihydroquinazolin-4-one; 8-Ethoxy-7-hydroxy-2-isopropyl-3-(4-cyanophenyl)-3,4-dihydroquinazolin-4-one; 4-(8-Ethoxy-7-hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile; Quinazolinone derivative 871814-30-1; 3-(4-Cyanobenzyl)-8-ethoxy-7-hydroxy-2-isopropylquinazolin-4(3H)-one (tautomeric form).
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles to meet your specific R&D or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.