Description

4(3H)-Quinazolinone, 3-(4-Chlorophenyl)-7-Hydroxy-8-(1-Methylethoxy)-2-(1-Methylethyl)- is a high-purity, synthetically derived quinazolinone derivative, a privileged scaffold in medicinal chemistry. This compound matters as a critical pharmaceutical intermediate for research and development, offering a versatile building block for creating novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity.
• Kinase Inhibitor Development: Explored in the synthesis of potential inhibitors targeting specific kinase enzymes involved in disease pathways.
• Anticancer Agent Research: Investigated for its potential utility in creating novel chemotherapeutic candidates.
• Anti-inflammatory Compound Synthesis: Utilized in research programs aimed at developing new anti-inflammatory drugs.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke chemical synthesis projects and scale-up processes under cGMP guidelines.

Basic Information

Product Name	4(3H)-Quinazolinone, 3-(4-Chlorophenyl)-7-Hydroxy-8-(1-Methylethoxy)-2-(1-Methylethyl)-
CAS No.	871814-23-2
Molecular Formula	C20H21ClN2O3
Molecular Weight	372.84 g/mol
Synonyms	3-(4-Chlorophenyl)-7-hydroxy-8-isopropoxy-2-isopropylquinazolin-4(3H)-one; 7-Hydroxy-8-isopropoxy-2-isopropyl-3-(4-chlorophenyl)-4(3H)-quinazolinone; 3-(p-Chlorophenyl)-7-hydroxy-8-isopropoxy-2-isopropyl-4(3H)-quinazolinone; 871814-23-2; Quinazolin-4(3H)-one, 3-(4-chlorophenyl)-7-hydroxy-8-(1-methylethoxy)-2-(1-methylethyl)-; 3-(4-Chlorophenyl)-7-hydroxy-8-(propan-2-yloxy)-2-(propan-2-yl)quinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports development work from discovery through to pre-clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.