Description

4(3H)-Quinazolinone, 3-(4-Chlorophenyl)-8-(Cyclopropylmethoxy)-7-Hydroxy-2-(1-Methylethyl)- is a high-purity, synthetically derived quinazolinone derivative, serving as a critical advanced pharmaceutical intermediate. Its complex molecular architecture, featuring a chlorophenyl and a cyclopropylmethoxy substituent, makes it a valuable scaffold for medicinal chemistry research and development. This compound is primarily targeted at R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Kinase Inhibitor Development: Potential precursor in the synthesis of small-molecule inhibitors due to the quinazolinone core's affinity for ATP-binding sites.
• Agrochemical Active Ingredient Synthesis: Intermediate in the development of new herbicides or fungicides.
• Biochemical Tool Compound: Used in vitro to study specific biological pathways and mechanisms of action.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and development.

Basic Information

Product Name	4(3H)-Quinazolinone, 3-(4-Chlorophenyl)-8-(Cyclopropylmethoxy)-7-Hydroxy-2-(1-Methylethyl)-
CAS No.	871814-22-1
Molecular Formula	C21H21ClN2O3
Molecular Weight	384.86 g/mol
Synonyms	3-(4-Chlorophenyl)-8-(cyclopropylmethoxy)-7-hydroxy-2-isopropylquinazolin-4(3H)-one; 7-Hydroxy-3-(4-chlorophenyl)-8-(cyclopropylmethoxy)-2-(1-methylethyl)-4(3H)-quinazolinone; 3-(p-Chlorophenyl)-8-(cyclopropylmethoxy)-7-hydroxy-2-isopropyl-4(3H)-quinazolinone; 871814-22-1; UNII-8V6T5F5B8F
EINECS	Contact for details

Quality Control

Every batch of our 4(3H)-Quinazolinone derivative is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and consistency to meet the exacting standards of pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing results for identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.