Description

2-Chloro-3-Methyl-3,4-Dihydroquinazolin-4-One is a high-purity, synthetically valuable heterocyclic building block. This compound is a key intermediate in the research and development of novel pharmaceutical agents, particularly in the creation of kinase inhibitors and other bioactive molecules. It is essential for medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic candidates. Its defined structure offers a precise starting point for further functionalization and structure-activity relationship studies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, especially for kinase-targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and the development of novel heterocyclic compounds for biological screening.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for specialized chemical products.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes conducting synthetic organic chemistry and drug discovery projects.

Basic Information

Item	Details
Product Name	2-Chloro-3-Methyl-3,4-Dihydroquinazolin-4-One
CAS No.	871548-31-1
Molecular Formula	C9H7ClN2O
Molecular Weight	194.62 g/mol
Synonyms	2-Chloro-3-methyl-3,4-dihydro-4-quinazolinone; 2-Chloro-3-methyl-4(3H)-quinazolinone; 3,4-Dihydro-2-chloro-3-methyl-4-quinazolinone; 4(3H)-Quinazolinone, 2-chloro-3-methyl-3,4-dihydro-; Quinazolin-4(3H)-one, 2-chloro-3-methyl-3,4-dihydro-; CAS 871548-31-1
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Methyl-3,4-Dihydroquinazolin-4-One is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for advanced research and development. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics is supplied with each shipment. Our quality protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.