Description

3-[4-(Pyrrolidin-1-Ylsulfonyl)Phenyl]Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a phenylpropanoic acid scaffold linked to a pyrrolidine sulfonamide moiety. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for the synthesis of enzyme inhibitors and targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially enzyme inhibitors targeting various disease pathways.
• Bioconjugation & Probe Development: Used to create chemical probes and affinity labels for biochemical and pharmacological research due to its reactive carboxylic acid group.
• Peptidomimetics & Medicinal Chemistry: Incorporated into peptide analogs and small molecules to modulate pharmacokinetic properties and biological activity.
• Chemical Biology Research: Serves as a versatile building block for constructing compound libraries used in high-throughput screening (HTS) campaigns.
• Material Science: Potential monomer or additive for creating specialized polymers with unique sulfonamide functionalities.

Basic Information

Item	Detail
Product Name	3-[4-(Pyrrolidin-1-Ylsulfonyl)Phenyl]Propanoic Acid
CAS No.	871544-58-0
Molecular Formula	C₁₃H₁₇NO₄S
Molecular Weight	283.34 g/mol
Synonyms	4-(Pyrrolidine-1-sulfonyl)hydrocinnamic Acid; 3-[4-(1-Pyrrolidinylsulfonyl)phenyl]propanoic Acid; 3-(4-(Pyrrolidine-1-sulfonyl)phenyl)propanoic Acid; 871544-58-0; Benzenepropanoic acid, 4-(1-pyrrolidinylsulfonyl)-; Pyrrolidine-1-sulfonylphenylpropanoic Acid
EINECS	Contact for details

Quality Control

Our 3-[4-(Pyrrolidin-1-Ylsulfonyl)Phenyl]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.