Description

(7-Chlorothiazolo[5,4-D]Pyrimidin-2-Yl)-p-Tolyl-Amine is a high-purity heterocyclic organic compound featuring a fused thiazolopyrimidine core structure. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, particularly for its role as a key building block in synthesizing novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors to create potential drug candidates targeting various disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel small molecule drugs, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Probe Development: Acts as a core structure for developing tool compounds to study specific biological targets and pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development programs for client companies.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	(7-Chlorothiazolo[5,4-D]Pyrimidin-2-Yl)-p-Tolyl-Amine
CAS No.	871266-80-7
Molecular Formula	C12H7ClN4S
Molecular Weight	274.73 g/mol
Synonyms	7-Chloro-2-(p-tolylamino)thiazolo[5,4-d]pyrimidine; 2-[(4-Methylphenyl)amino]-7-chlorothiazolo[5,4-d]pyrimidine; 7-Chloro-N-(4-methylphenyl)thiazolo[5,4-d]pyrimidin-2-amine; (7-Chloro-thiazolo[5,4-d]pyrimidin-2-yl)-p-tolyl-amine; 871266-80-7; Thiazolo[5,4-d]pyrimidine, 7-chloro-2-[(4-methylphenyl)amino]-; p-Tolyl-(7-chlorothiazolo[5,4-d]pyrimidin-2-yl)amine
EINECS	Contact for details

Quality Control

Our (7-Chlorothiazolo[5,4-D]Pyrimidin-2-Yl)-p-Tolyl-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.