Description

7,8-Dichloro-4-Hydroxyquinoline is a halogenated hydroxyquinoline derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or possessing chelating properties.
• Agrochemical Research: Used in the development of new fungicides or herbicides, leveraging the bioactive quinoline core structure.
• Coordination Chemistry & Chelation: Acts as a ligand for metal ions, useful in creating catalysts or metal-organic frameworks (MOFs) for various industrial processes.
• Material Science Precursor: Employed in the synthesis of organic electronic materials or fluorescent dyes due to its conjugated quinoline system.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study biological pathways and enzyme functions.
• Academic & Institutional Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	7,8-Dichloro-4-Hydroxyquinoline
CAS No.	871217-91-3
Molecular Formula	C9H5Cl2NO
Molecular Weight	214.05 g/mol
Synonyms	4-Hydroxy-7,8-dichloroquinoline; 7,8-Dichloro-4-quinolinol; 4-Hydroxy-7,8-dichloro-quinoline; 7,8-Dichloro-4-hydroxy-quinoline; 7,8-Dichloro-4(1H)-quinolinone (tautomer); 4-Quinolinol, 7,8-dichloro-; Dichlorohydroxyquinoline
EINECS	Contact for details

Quality Control

Our 7,8-Dichloro-4-Hydroxyquinoline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.