Description

4-[(3R)-3-Amino-1-Oxo-4-(Phenylthio)Butyl]Morpholine is a high-purity chiral building block and advanced pharmaceutical intermediate of significant commercial importance. Its value lies in its specific stereochemistry and functional groups, which make it a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and production of novel therapeutic agents, particularly in areas requiring sophisticated organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of proprietary drug candidates and complex APIs.
• Organic Synthesis Building Block: Utilized in research and development for constructing complex molecular architectures, particularly those containing morpholine and thioether functionalities.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	4-[(3R)-3-Amino-1-Oxo-4-(Phenylthio)Butyl]Morpholine
CAS No.	870812-94-5
Molecular Formula	C14H20N2O2S
Molecular Weight	280.39 g/mol
Synonyms	(R)-4-(3-Amino-1-oxo-4-(phenylthio)butyl)morpholine; 4-[(3R)-3-Amino-1-oxo-4-(phenylsulfanyl)butyl]morpholine; 870812-94-5; (R)-4-(3-Amino-1-oxo-4-(phenylthio)butyl)morpholine; Morpholine, 4-[(3R)-3-amino-1-oxo-4-(phenylthio)butyl]-; 4-[(3R)-3-Amino-1-oxo-4-(phenylsulfanyl)butyl]tetrahydro-2H-1,4-oxazine
EINECS	Contact for details

Quality Control

Our 4-[(3R)-3-Amino-1-Oxo-4-(Phenylthio)Butyl]Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep the container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.