Description

2-(2-Chloro-6-Fluorophenyl)Ethylamine H& is a versatile halogenated aromatic amine building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the phenyl ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents and receptor-targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the chloro-fluoro-phenyl moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials that require specific halogenated aromatic components.
• Custom Synthesis and Contract Manufacturing: A high-value starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Product Name	2-(2-Chloro-6-Fluorophenyl)Ethylamine H&
CAS No.	870717-94-5
Molecular Formula	C8H9ClFN
Molecular Weight	173.61 g/mol
Synonyms	2-(2-Chloro-6-fluorophenyl)ethan-1-amine; 1-(2-Chloro-6-fluorophenyl)ethanamine; 2-(2-Chloro-6-fluorophenyl)ethylamine; 2-Chloro-6-fluoro-β-phenethylamine; 2-Chloro-6-fluorophenethylamine; (2-Chloro-6-fluorophenyl)ethylamine; 870717-94-5
EINECS	Contact for details

Quality Control

Our production of 2-(2-Chloro-6-Fluorophenyl)Ethylamine H& adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.