Description

(2-Chloro-Pyridin-3-Yl)-Methylamine Dihydrochloride is a high-purity, versatile chemical building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized pyridine core, which serves as a critical intermediate for constructing complex molecules with targeted biological or material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the chloropyridine moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Chemical Biology Probe Synthesis: Employed in the construction of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	(2-Chloro-Pyridin-3-Yl)-Methylamine Dihydrochloride
CAS No.	870064-16-7
Molecular Formula	C6H8Cl2N2 • 2HCl
Molecular Weight	215.96 g/mol (Free base: 142.59 g/mol)
Synonyms	1-(2-Chloropyridin-3-yl)methanamine dihydrochloride; 2-Chloro-3-(aminomethyl)pyridine dihydrochloride; (2-Chloro-3-pyridinyl)methylamine dihydrochloride; 3-(Aminomethyl)-2-chloropyridine dihydrochloride; 2-Chloro-3-pyridinemethanamine dihydrochloride; 2-Chloro-3-(aminomethyl)pyridine hydrochloride (1:2); 870064-16-7
EINECS	Contact for details

Quality Control

Our (2-Chloro-Pyridin-3-Yl)-Methylamine Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.