Description

1-Isobutyryl-1,2,3,4-Tetrahydroquinolin-6-Amine is a high-purity, advanced pharmaceutical intermediate (API intermediate) with the CAS number 869945-53-9. This compound is a key building block in the synthesis of complex organic molecules, valued for its specific tetrahydroquinoline scaffold and amine functionality. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a key building block for developing new pesticides and herbicides with enhanced efficacy.
• Organic Synthesis & Research: Used in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new chemical reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring the tetrahydroquinoline structure.

Basic Information

Product Name	1-Isobutyryl-1,2,3,4-Tetrahydroquinolin-6-Amine
CAS No.	869945-53-9
Molecular Formula	C₁₃H₁₈N₂O
Molecular Weight	218.30 g/mol
Synonyms	6-Amino-1-isobutyryl-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-6-quinolinamine, 1-(2-methyl-1-oxopropyl)-; 869945-53-9; 1-(2-Methylpropanoyl)-1,2,3,4-tetrahydroquinolin-6-amine; 1-Isobutyryl-6-amino-1,2,3,4-tetrahydroquinoline; 6-Amino-1-(2-methylpropionyl)-1,2,3,4-tetrahydroquinoline
EINECS	Contact for details

Quality Control

Our 1-Isobutyryl-1,2,3,4-Tetrahydroquinolin-6-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, impurity profile, and residual solvents, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.