Description

2-Bromo-5-(Trifluoromethyl)-Benzenepropanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its bromine and trifluoromethyl functional groups. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of novel organic electronic materials and liquid crystals due to its unique electronic properties imparted by the halogen and fluorine atoms.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromo-5-(Trifluoromethyl)-Benzenepropanoic Acid
CAS No.	869725-56-4
Molecular Formula	C10H8BrF3O2
Molecular Weight	297.07 g/mol
Synonyms	3-[2-Bromo-5-(trifluoromethyl)phenyl]propanoic acid; Benzenepropanoic acid, 2-bromo-5-(trifluoromethyl)-; 2-Bromo-5-(trifluoromethyl)benzenepropanoic acid; 2-Bromo-α,α,α-trifluoro-m-toluic acid, ω-carboxyethyl derivative; (2-Bromo-5-trifluoromethylphenyl)propionic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-(Trifluoromethyl)-Benzenepropanoic Acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and purity. Our standard grade meets high-purity requirements suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.