Description

4-Bromo-2-Chloro-1-(Cyclopropyloxy)Benzene is a high-purity halogenated aromatic ether building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialized polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions due to the bromo and chloro substituents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.
• Organic Synthesis Building Block: Provides a versatile scaffold for introducing cyclopropyl and halogen functionalities into target molecules.

Basic Information

Product Name	4-Bromo-2-Chloro-1-(Cyclopropyloxy)Benzene
CAS No.	869569-68-6
Molecular Formula	C9H8BrClO
Molecular Weight	247.52 g/mol
Synonyms	1-Bromo-4-chloro-2-(cyclopropyloxy)benzene; 2-Chloro-4-bromophenyl cyclopropyl ether; Benzene, 4-bromo-2-chloro-1-(cyclopropyloxy)-; 4-Bromo-2-chlorophenyl cyclopropyl ether; Cyclopropyl 4-bromo-2-chlorophenyl ether
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-1-(Cyclopropyloxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.