Description

(5-Chloro-2-Iodophenyl) 2,6-Difluorophenyl Methano is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring chlorine, iodine, and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by R&D and process development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen pattern can enhance biological activity and environmental stability.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals with specific optical or electronic characteristics.
• Ligand and Catalyst Development: Employed in the design of sophisticated organocatalysts and metal-organic frameworks (MOFs) for asymmetric synthesis and gas separation processes.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme mechanisms and protein-ligand interactions due to its potential as a radiolabeling or fluorescent tagging scaffold.

Basic Information

Product Name	(5-Chloro-2-Iodophenyl) 2,6-Difluorophenyl Methano
CAS No.	869365-97-9
Molecular Formula	C13H6ClF2IO
Molecular Weight	378.54 g/mol
Synonyms	2,6-Difluorobenzoyl(5-chloro-2-iodobenzene); (5-Chloro-2-iodophenyl)(2,6-difluorophenyl)methanone; Methanone, (5-chloro-2-iodophenyl)(2,6-difluorophenyl)-; 869365-97-9; 5-Chloro-2-iodophenyl 2,6-difluorophenyl ketone; 2,6-Difluoro-5'-chloro-2'-iodobenzophenone
EINECS	Contact for details

Quality Control

Our production of (5-Chloro-2-Iodophenyl) 2,6-Difluorophenyl Methano adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established analytical methods, including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.