Description

2-Quinazolinecarboxylic Acid, 6-Chloro-5-Fluoro-3,4-Dihydro-4-Oxo-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific quinazoline core structure. This compound is of critical importance for its role as a key building block in the synthesis of novel, potent active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those targeting specific enzymatic pathways.
• API Synthesis: Serves as a core scaffold for the development of new Active Pharmaceutical Ingredients (APIs), especially in oncology and antiviral research.
• Agrochemical Research: Used in the research and development of next-generation herbicides and pesticides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Employed in academic and industrial research to create probes for studying biological processes and target validation.
• Organic Synthesis Building Block: Utilized in custom synthesis and medicinal chemistry for constructing complex molecular architectures.

Basic Information

Product Name	2-Quinazolinecarboxylic Acid, 6-Chloro-5-Fluoro-3,4-Dihydro-4-Oxo-, Ethyl Ester
CAS No.	869297-83-6
Molecular Formula	C12H10ClFN2O3
Molecular Weight	284.67 g/mol
Synonyms	Ethyl 6-Chloro-5-fluoro-4-oxo-3,4-dihydroquinazoline-2-carboxylate; 6-Chloro-5-fluoro-4-oxo-3,4-dihydroquinazoline-2-carboxylic acid ethyl ester; 869297-83-6; Quinazoline-2-carboxylic acid, 6-chloro-5-fluoro-3,4-dihydro-4-oxo-, ethyl ester; Ethyl 6-chloro-5-fluoro-4-oxo-1,4-dihydroquinazoline-2-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Quinazolinecarboxylic Acid, 6-Chloro-5-Fluoro-3,4-Dihydro-4-Oxo-, Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.