Description

Picamilone is a synthetic nootropic compound belonging to the class of GABA derivatives, specifically designed to enhance cognitive function and cerebral blood flow. Its primary value lies in its unique mechanism of action, which combines GABAergic activity with vasodilation properties, making it a compound of significant interest for neurological research and development. This product is essential for pharmaceutical R&D teams, academic researchers, and manufacturers focused on neurosciences, cognitive enhancers, and neuroprotective agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor or active ingredient in the development of novel nootropic and neuroprotective medications.
• Neurological Research: Used in preclinical and clinical studies to investigate mechanisms related to cerebral ischemia, cognitive enhancement, and neurovascular coupling.
• Dietary Supplement Formulation: Incorporated into advanced nutraceutical products aimed at supporting memory, focus, and overall brain health (subject to regional regulations).
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Bioavailability Studies: Utilized in pharmacokinetic and pharmacodynamic research to understand absorption and metabolism profiles.

Basic Information

Product Name	Picamilone
CAS No.	869277-81-6
Molecular Formula	C9H14N2O3
Molecular Weight	198.22 g/mol
Synonyms	N-Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid; Picamilon; Pikamilon; GABA Nicotinate; N-(3-Carbamoylpyridin-1-ium-1-yl)butanoate; Gidazepam Impurity; 4-[[(Pyridine-3-carbonyl)amino]]butanoic acid
EINECS	Contact for details

Quality Control

Every batch of our Picamilone is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) that include results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.