Description

Memantine CAS NO 19982-08-2 is a high-purity pharmaceutical active ingredient belonging to the adamantane derivative class. It is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, primarily valued for its neuroprotective properties and role in managing neurological conditions. This compound is essential for manufacturers in the pharmaceutical industry developing treatments for cognitive disorders. We supply it with a focus on stringent quality control to ensure batch-to-batch consistency for reliable formulation.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of medications for Alzheimer's disease and other forms of dementia.
• Neurological Research as a reference standard or investigational compound in studies of NMDA receptor function and neuroprotection.
• Formulation Development for solid oral dosage forms such as tablets and capsules.
• Generic Drug Production for cost-effective alternatives to branded neurological therapies.
• Chemical Intermediate for the synthesis of more complex pharmaceutical molecules or derivatives.
• Veterinary Pharmaceutical Applications in research for cognitive dysfunction in animals.

Basic Information

Product Name	Memantine
CAS No.	19982-08-2
Molecular Formula	C12H21N
Molecular Weight	179.30 g/mol
Synonyms	Memantine Hydrochloride (common salt form); 1-Amino-3,5-dimethyladamantane; 3,5-Dimethyl-1-adamantanamine; 3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-amine; Akatinol; Ebixa; Namenda; D-145; DMAA
EINECS	243-415-0

Quality Control

Our Memantine is produced and tested under a GMP-compliant quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets stringent purity and identity criteria, typically referencing USP, EP, or in-house pharmaceutical-grade specifications. A detailed Certificate of Analysis (COA) documenting results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 20 ppm
Loss on Drying	< 1.0%
Sulfated Ash	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.