Description

N-(3-Chloro-4-Fluorophenyl)-N-(7-Methoxy-6-Nitroquinazolin-4-yl)Acetamide is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists working on targeted kinase inhibitors and novel therapeutic agents. It is primarily utilized in the synthesis of active pharmaceutical ingredients (APIs) within the pharmaceutical and biotechnology sectors, where precise molecular structure and purity are paramount for successful drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinazoline-based kinase inhibitors for oncology research.
• Drug Discovery & Development: Used in high-throughput screening and lead optimization studies to develop new therapeutic candidates.
• Biochemical Research: Serves as a reference standard or a probe compound in enzymatic assays and target validation studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of investigational new drugs.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and pharmacology.

Basic Information

Product Name	N-(3-Chloro-4-Fluorophenyl)-N-(7-Methoxy-6-Nitroquinazolin-4-yl)Acetamide
CAS No.	869199-61-1
Molecular Formula	C₁₇H₁₂ClFN₄O₄
Molecular Weight	402.75 g/mol
Synonyms	869199-61-1; N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-nitro-4-quinazolinyl)acetamide; Acetamide, N-(3-chloro-4-fluorophenyl)-N-(7-methoxy-6-nitro-4-quinazolinyl)-; 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-N-(7-methoxy-6-nitro-4-quinazolinyl)acetamide deriv.; 3-Chloro-4-fluoro-N-(7-methoxy-6-nitroquinazolin-4-yl)-N-phenylacetamide
EINECS	Contact for details

Quality Control

Our N-(3-Chloro-4-Fluorophenyl)-N-(7-Methoxy-6-Nitroquinazolin-4-yl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.