Description

2-Oxiranemethanol, 3-(Azidomethyl)- is a highly functionalized epoxide derivative, also known as Glycidyl Azide, characterized by the presence of both an oxirane ring and an azide group. This unique bifunctional structure makes it a valuable click chemistry intermediate and a versatile building block for the synthesis of complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel compounds and polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those utilizing Huisgen cycloaddition (click chemistry) for bioconjugation.
• Polymer & Resin Modification: Used to introduce azide functionality into polymer backbones (e.g., epoxy resins, polyethers) for subsequent cross-linking or functionalization, enhancing material properties.
• Agrochemical Synthesis: Acts as a building block for creating novel herbicides, fungicides, and insecticides with tailored efficacy and environmental profiles.
• Energetic Materials Research: Employed in the development of advanced propellants and explosives due to its high nitrogen content and energetic azide group.
• Surface Chemistry & Bioconjugation: Facilitates the covalent attachment of biomolecules (e.g., proteins, peptides) to surfaces, nanoparticles, or other polymers for diagnostic and therapeutic applications.
• Cross-linking Agent: Functions as a cross-linker in specialty coatings, adhesives, and sealants to improve thermal stability and mechanical strength.

Basic Information

Product Name	2-Oxiranemethanol, 3-(Azidomethyl)-
CAS No.	868684-49-5
Molecular Formula	C4H7N3O2
Molecular Weight	129.12 g/mol
Synonyms	Glycidyl Azide; 3-Azidomethyloxiranemethanol; 1-Azido-3-hydroxy-2-propylene oxide; Azidomethyl Oxiranylmethanol; (Oxiran-2-yl)methanol, 3-(azidomethyl)-; GA; Glycidyl Azide Monomer; 2,3-Epoxypropyl Azide
EINECS	Contact for details

Quality Control

Our production of 2-Oxiranemethanol, 3-(Azidomethyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is analyzed using advanced techniques including HPLC, NMR, and FTIR to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We operate under a cGMP-compliant quality management system to meet the exacting standards of pharmaceutical and advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C/59-77°F). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, open flames, and incompatible materials such as strong reducing agents. For long-term storage, consider storing under an inert gas (e.g., nitrogen or argon) in a freezer (-20°C).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Gravity (20°C)	1.20 - 1.30

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.