Description

2-Trifluoromethylquinoline-6-Carbonitrile is a high-value fluorinated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and nitrile functional groups make it an indispensable intermediate for creating compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science Precursor: Employed in the synthesis of functional organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: An important compound for exploring novel fluorination reactions and the properties of fluorinated heterocycles.

Basic Information

Product Name	2-Trifluoromethylquinoline-6-Carbonitrile
CAS No.	868662-64-0
Molecular Formula	C11H5F3N2
Molecular Weight	222.17 g/mol
Synonyms	6-Cyano-2-(trifluoromethyl)quinoline; Quinoline-6-carbonitrile, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)-6-quinolinecarbonitrile; 2-Trifluoromethyl-6-cyanoquinoline; 868662-64-0; 2-Trifluoromethylquinoline-6-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethylquinoline-6-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for each shipment, supporting your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.