Description

1-(9-Fluorenylmethyloxycarbonyl-Amino)-4,7,10-Trioxa-13-Tridecanamine Hydrochloride is a specialized, high-purity chemical building block designed for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise, reliable intermediates for complex molecular assembly. It is primarily utilized in the development of novel pharmaceuticals, bioconjugates, and sophisticated materials where controlled functionalization is paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected polyether amine linker for the controlled assembly of peptide chains and peptide-drug conjugates.
• Bioconjugation & Linker Chemistry: For attaching therapeutic payloads, fluorophores, or targeting moieties to antibodies, proteins, or nanoparticles via its amine functionality.
• Dendrimer & Polymer Synthesis: Serving as a versatile branching unit or functional monomer for constructing well-defined dendritic structures and functional polymers.
• Prodrug Development: Used to create cleavable linkers that improve drug solubility, stability, and targeted release profiles.
• Material Science & Surface Modification: For introducing hydrophilic polyether spacers and reactive amine groups onto surfaces or materials to alter their physicochemical properties.
• Chemical Biology Probes: In the synthesis of probes for studying biological processes, leveraging its orthogonal protecting group strategy and solubility characteristics.

Basic Information

Product Name	1-(9-Fluorenylmethyloxycarbonyl-Amino)-4,7,10-Trioxa-13-Tridecanamine Hydrochloride
CAS No.	868599-75-1
Molecular Formula	C28H39N2O6Cl
Molecular Weight	535.07 g/mol
Synonyms	Fmoc-N-amido-PEG3-amine hydrochloride; 1-(Fmoc-amino)-4,7,10-trioxa-13-tridecanamine hydrochloride; Fmoc-NH-PEG3-NH2·HCl; Nα-Fmoc-3,6,9-trioxa-12-azatetradecane-1,14-diamine hydrochloride; 14-Amino-3,6,9-trioxa-12-azatetradecan-1-aminium, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, chloride (1:1); Fmoc-15-amino-4,7,10-trioxapentadecylamine hydrochloride; Fmoc protected triethylene glycol diamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(9-Fluorenylmethyloxycarbonyl-Amino)-4,7,10-Trioxa-13-Tridecanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.