Description

4-Bromo-2-[(2,4,5-Trifluoroanilino)Methyl]Benzenol is a specialized halogenated aniline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring bromine and fluorine substituents, makes it a valuable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders or as kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the trifluoromethylaniline moiety can enhance biological activity and metabolic stability.
• Material Science: Building block for creating advanced organic electronic materials, such as charge-transport layers or organic light-emitting diodes (OLEDs).
• Ligand Synthesis: Serves as a starting material for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: Utilized in the design of fluorescent dyes and molecular probes for bioimaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	4-Bromo-2-[(2,4,5-Trifluoroanilino)Methyl]Benzenol
CAS No.	868256-54-6
Molecular Formula	C13H8BrF3NO
Molecular Weight	334.11 g/mol
Synonyms	4-Bromo-2-[(2,4,5-trifluoroanilino)methyl]phenol; 2-[(2,4,5-Trifluoroanilino)methyl]-4-bromophenol; 4-Bromo-2-[(2,4,5-trifluorophenylamino)methyl]phenol; Benzenol, 4-bromo-2-[(2,4,5-trifluoroanilino)methyl]-; 868256-54-6; 4-Bromo-2-((2,4,5-trifluoroanilino)methyl)phenol; 2-(Aminomethyl)-4-bromophenol, N-(2,4,5-trifluorophenyl)- derivative
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-[(2,4,5-Trifluoroanilino)Methyl]Benzenol adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with global regulatory frameworks, including REACH, and can supply materials suitable for GMP (Good Manufacturing Practice) applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.