Description

2,2-Difluoropropylamine Hydrochloride is a high-purity fluorinated amine salt serving as a critical building block in advanced organic synthesis. This compound matters for its role in introducing the difluoromethyl group, a key moiety for modulating the physicochemical and metabolic properties of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including potential protease inhibitors and herbicides.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting enzymatic pathways.
• Agrochemical Synthesis: Used in creating novel herbicides and pesticides where the difluoromethyl group enhances biological activity and environmental stability.
• Fluorinated Building Block: Essential for medicinal chemistry projects aimed at improving drug lipophilicity, metabolic stability, and bioavailability through strategic fluorination.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new reactions and synthesizing complex fluorinated organic molecules.
• Ligand and Catalyst Preparation: Can be utilized in the synthesis of specialized ligands or catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2,2-Difluoropropylamine Hydrochloride
CAS No.	868241-48-9
Molecular Formula	C3H7ClF2N
Molecular Weight	130.54 g/mol
Synonyms	2,2-Difluoropropan-1-amine hydrochloride; 1-Amino-2,2-difluoropropane hydrochloride; 2,2-Difluoro-1-propanamine hydrochloride; 2,2-Difluoropropylammonium chloride; Propylamine, 2,2-difluoro-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2,2-Difluoropropylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.