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Udp-6-Azido-6-Deoxy-D-Gal.2Na CAS NO 868208-96-2
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CAS No.:868208-96-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Udp-6-Azido-6-Deoxy-D-Gal.2Na is a specialized nucleotide sugar derivative, a crucial biochemical tool for studying and manipulating glycosylation pathways. This compound serves as a key metabolic precursor for the enzymatic synthesis of azido-labeled glycoconjugates, enabling bioorthogonal click chemistry applications. It is primarily utilized by researchers and developers in the fields of glycobiology, chemical biology, and pharmaceutical development for probe synthesis and metabolic glycan engineering.
Application
- Metabolic Glycan Engineering: Acts as a biosynthetic precursor for incorporating azide tags into cell surface glycans for subsequent labeling via click chemistry (e.g., CuAAC, SPAAC).
- Glycoconjugate Synthesis: Used as a substrate for glycosyltransferases in the in vitro enzymatic synthesis of azido-functionalized oligosaccharides, glycoproteins, or glycolipids.
- Chemical Biology Probes: Enables the creation of activity-based probes to study the function of specific glycosyltransferases and other carbohydrate-active enzymes.
- Drug Discovery & Development: Facilitates the synthesis of novel glycomimetics and glycotherapeutic candidates with modified biological activity and stability.
- Diagnostic Reagent Development: Serves as a key intermediate in producing labeled reagents for glycan array fabrication and other diagnostic platforms.
- Academic & Industrial Research: A fundamental reagent for investigating carbohydrate metabolism, cell-surface engineering, and host-pathogen interactions.
Basic Information
| Product Name | Udp-6-Azido-6-Deoxy-D-Gal.2Na |
| CAS No. | 868208-96-2 |
| Molecular Formula | C15H21N5O16P2 • 2Na |
| Molecular Weight | 659.28 g/mol (Disodium Salt) |
| Synonyms | UDP-6-azido-6-deoxy-D-galactose disodium salt; UDP-6-N3-Gal; Uridine 5'-diphospho-6-azido-6-deoxy-D-galactose disodium salt; 6-Azido-6-deoxy-UDP-galactose; UDP-α-D-galactopyranosyl-6-azide disodium salt; UDP-Gal-6-N3 (2Na); Uridine diphosphate 6-azidogalactose |
| EINECS | Contact for details |
Quality Control
Our Udp-6-Azido-6-Deoxy-D-Gal.2Na is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the exacting standards required for sensitive biochemical and research applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0% |
| Endotoxin | < 10 EU/mg |
| Biological Activity | Functional as glycosyltransferase substrate |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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