Description

3-Fluoro-3'-Methoxy[1,1'-Biphenyl]-4-Amine is a high-purity, functionalized biphenyl derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical pharmaceutical intermediate for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its biphenyl core for biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced organic electronic materials and liquid crystal compounds due to its rigid, substituted biphenyl structure.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalysis and asymmetric synthesis.
• Polymer & Resin Modifier: Acts as a functional monomer or cross-linking agent to impart specific properties like thermal stability or fluorescence to advanced polymers.
• Academic & Contract Research: Essential for fundamental organic chemistry research and custom synthesis projects in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	3-Fluoro-3'-Methoxy[1,1'-Biphenyl]-4-Amine
CAS No.	867287-99-8
Molecular Formula	C13H12FNO
Molecular Weight	217.24 g/mol
Synonyms	[1,1'-Biphenyl]-4-amine, 3-fluoro-3'-methoxy-; 3-Fluoro-3'-methoxybiphenyl-4-amine; 4-Amino-3-fluoro-3'-methoxybiphenyl; 3'-Methoxy-3-fluoro[1,1'-biphenyl]-4-amine; 3-Fluoro-3'-methoxy-4-aminobiphenyl; NSC 796096; Amine 867287-99-8
EINECS	Contact for details

Quality Control

Our 3-Fluoro-3'-Methoxy[1,1'-Biphenyl]-4-Amine is manufactured under a cGMP-compliant quality management system to ensure batch-to-batch consistency and high purity. Every lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to confirm identity, potency, and impurity profiles. Comprehensive Certificates of Analysis (COA) documenting all specifications are provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.