Description

2-Iodophenylmethylthioacetic Acid is a versatile organosulfur and organoiodine building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a thioacetic acid moiety and an iodine substituent on an aromatic ring, makes it a critical precursor for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the synthesis of novel heterocycles.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for molecules requiring aryl-iodide or thioether linkages.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the iodine atom enables efficient palladium-catalyzed cross-coupling for structure diversification.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialized polymers and advanced organic materials with unique electronic or structural properties.
• Ligand and Catalyst Preparation: Employed for synthesizing custom ligands for transition metal catalysis, leveraging the reactivity of both the iodine and sulfur functionalities.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological pathways, where the iodine can serve as a handle for further modification or radiolabeling.

Basic Information

Product Name	2-Iodophenylmethylthioacetic Acid
CAS No.	867202-85-5
Molecular Formula	C9H9IO2S
Molecular Weight	308.14 g/mol
Synonyms	2-(2-Iodophenylthio)acetic Acid; (2-Iodophenylthio)acetic Acid; α-[(2-Iodophenyl)thio]acetic Acid; 2-[(2-Iodophenyl)sulfanyl]acetic Acid; 2-Iodobenzenethiolacetic Acid; o-Iodophenylthioacetic Acid; 867202-85-5; Methylthioacetic Acid, 2-Iodophenyl-
EINECS	Contact for details

Quality Control

Every batch of 2-Iodophenylmethylthioacetic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) specifying identity, purity (typically by HPLC), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.