Description

4-Chloro-2-Methyl-6-Trifluoromethylquinoline is a high-purity, multi-functional quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical synthetic intermediate, valued for its unique halogenated and trifluoromethylated structure which imparts desirable electronic and steric properties to target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Employed in the creation of organic semiconductors, light-emitting diodes (OLEDs), and other advanced electronic materials due to its electron-deficient quinoline core.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis for cross-coupling and other organic transformations.
• Fluorescent Probe Synthesis: Utilized in the design of fluorescent dyes and molecular probes for bioimaging and diagnostic applications.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	4-Chloro-2-Methyl-6-Trifluoromethylquinoline
CAS No.	867167-05-3
Molecular Formula	C12H7ClF3N
Molecular Weight	257.64 g/mol
Synonyms	4-Chloro-2-methyl-6-(trifluoromethyl)quinoline; 6-(Trifluoromethyl)-4-chloro-2-methylquinoline; 2-Methyl-4-chloro-6-trifluoromethylquinoline; Quinoline, 4-chloro-2-methyl-6-(trifluoromethyl)-; 867167-05-3; 4-Chloro-2-methyl-6-trifluoromethyl-quinoline; 4-Chloro-2-methyl-6-(trifluoromethyl)quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-6-Trifluoromethylquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.