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3-(8-Chloro-1-(2-Phenylquinolin-7-Yl)Imidazo[1,5-A]Pyrazin-3-Yl)Cyclobutanone CAS NO 867165-62-6


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CAS No.:867165-62-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(8-Chloro-1-(2-Phenylquinolin-7-Yl)Imidazo[1,5-A]Pyrazin-3-Yl)Cyclobutanone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role in the research and development of novel therapeutic agents, particularly in oncology and targeted drug discovery. Pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers need this precise building block to synthesize and evaluate new chemical entities. Its defined structure is essential for ensuring the consistency and efficacy of downstream active pharmaceutical ingredients (APIs).

Application

  • Pharmaceutical Intermediate: A key synthetic precursor in the development of small-molecule drug candidates, particularly for kinase inhibitors and other targeted therapies.
  • Oncology Research: Used in medicinal chemistry programs focused on discovering new anti-cancer agents due to its imidazopyrazine-quinoline scaffold.
  • Chemical Biology Probes: Serves as a core structure for creating molecular probes to study specific enzyme functions and biological pathways.
  • Contract Research & Development (CRO/CDMO): Supplied to research partners for custom synthesis, process development, and scale-up activities.
  • Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and drug design.
  • Preclinical Development: Incorporated into compounds for pharmacological profiling, pharmacokinetic studies, and toxicology assessments.

Basic Information

Item Detail
Product Name 3-(8-Chloro-1-(2-Phenylquinolin-7-Yl)Imidazo[1,5-A]Pyrazin-3-Yl)Cyclobutanone
CAS No. 867165-62-6
Molecular Formula C29H19ClN4O
Molecular Weight 474.94 g/mol
Synonyms 3-(8-Chloro-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)cyclobutan-1-one; 867165-62-6; 3-(8-Chloro-1-(2-phenyl-7-quinolyl)imidazo[1,5-a]pyrazin-3-yl)cyclobutanone; Cyclobutanone, 3-[8-chloro-1-[2-phenyl-7-quinolinyl]imidazo[1,5-a]pyrazin-3-yl]-; 3-[8-Chloro-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanone
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Quality Control

Our 3-(8-Chloro-1-(2-Phenylquinolin-7-Yl)Imidazo[1,5-A]Pyrazin-3-Yl)Cyclobutanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance Off-white to light yellow solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Complies with ICH guidelines
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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