Description

7-Chloro-8-Fluoro-2-Phenylquinolin-4(1H)-One is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic quinoline core. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly in oncology and anti-infective therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing novel quinoline-based heterocyclic compounds.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents.

Basic Information

Product Name	7-Chloro-8-Fluoro-2-Phenylquinolin-4(1H)-One
CAS No.	867165-00-2
Molecular Formula	C15H9ClFNO
Molecular Weight	273.69 g/mol
Synonyms	7-Chloro-8-fluoro-2-phenyl-1,4-dihydroquinolin-4-one; 7-Chloro-8-fluoro-2-phenyl-4(1H)-quinolinone; 4(1H)-Quinolinone, 7-chloro-8-fluoro-2-phenyl-; 2-Phenyl-7-chloro-8-fluoro-4-quinolone; 7-Chloro-8-fluoro-2-phenylquinolin-4-ol; 867165-00-2
EINECS	Contact for details

Quality Control

Our 7-Chloro-8-Fluoro-2-Phenylquinolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.