Description

7-Chloro-8-Fluoro-2-Phenylquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated quinoline core fused with a phenyl substituent makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated quinoline scaffold.
• Material Science: Acts as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced functional materials.
• Chemical Biology: Employed as a molecular probe or scaffold in the design of enzyme inhibitors and receptor ligands.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploration of novel heterocyclic chemistry.
• Fine Chemical Synthesis: A versatile intermediate for creating more complex, value-added specialty chemicals.

Basic Information

Product Name	7-Chloro-8-Fluoro-2-Phenylquinoline
CAS No.	867164-92-9
Molecular Formula	C15H9ClFN
Molecular Weight	257.69 g/mol
Synonyms	2-Phenyl-7-chloro-8-fluoroquinoline; 7-Chloro-8-fluoro-2-phenylquinoline; Quinoline, 7-chloro-8-fluoro-2-phenyl-; 867164-92-9; 7-Chloro-8-fluoro-2-phenyl-quinoline; 2-Phenyl-8-fluoro-7-chloroquinoline; 8-Fluoro-7-chloro-2-phenylquinoline
EINECS	Contact for details

Quality Control

Our 7-Chloro-8-Fluoro-2-Phenylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.