Description

2H-Indazole-5-Methanamine, 4,5,6,7-Tetrahydro-, (+)- is a high-purity chiral amine derivative of the tetrahydroindazole class, serving as a critical building block in advanced organic synthesis. Its value lies in its unique stereochemistry and functional group, which are essential for constructing complex molecules with specific biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and pesticides, leveraging its heterocyclic structure.
• Chemical Biology Probe: Serves as a scaffold or precursor for developing molecular probes to study enzyme function and biological pathways.
• Asymmetric Catalysis Ligand Precursor: Its chiral amine structure can be utilized to develop novel ligands for asymmetric synthesis.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in synthetic organic chemistry.
• Fine Chemical Synthesis: A versatile intermediate for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2H-Indazole-5-Methanamine, 4,5,6,7-Tetrahydro-, (+)-
CAS No.	867023-70-9
Molecular Formula	C8H15N3
Molecular Weight	153.23 g/mol
Synonyms	(+)-4,5,6,7-Tetrahydro-2H-indazol-5-ylmethanamine; (5R)-4,5,6,7-Tetrahydro-2H-indazol-5-ylmethanamine; (R)-4,5,6,7-Tetrahydro-2H-indazol-5-ylmethanamine; (R)-5-(Aminomethyl)-4,5,6,7-tetrahydro-1H-indazole; 5-(Aminomethyl)-4,5,6,7-tetrahydro-2H-indazole, (R)-; UNII-9Q8F8QK3VH; 9Q8F8QK3VH; (R)-5-(Aminomethyl)-4,5,6,7-tetrahydro-2H-indazole
EINECS	Contact for details

Quality Control

Every batch of 2H-Indazole-5-Methanamine, 4,5,6,7-Tetrahydro-, (+)- is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity research standards, with comprehensive testing via HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.