Description

6-Bromo-1,1-(Ethylenedioxo)-Indane is a high-purity, specialized organic intermediate featuring a brominated indane core protected by an ethylenedioxy ketal group. This unique molecular architecture makes it a valuable and versatile building block for advanced synthetic chemistry, particularly in the development of complex pharmaceutical compounds and functional materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological pathways and protein interactions.
• Academic & Industrial R&D: A critical reagent for methodological development in organic synthesis, including cross-coupling reactions and ring-forming transformations.
• Fine Chemical Production: Used in the multi-step synthesis of complex fragrance and flavor ingredients.

Basic Information

Product Name	6-Bromo-1,1-(Ethylenedioxo)-Indane
CAS No.	866848-94-4
Molecular Formula	C₁₁H₁₁BrO₂
Molecular Weight	255.11 g/mol
Synonyms	6-Bromo-1,1-ethylenedioxyindane; 6-Bromo-2,3-dihydro-1H-indene-1,1-diyl diethyl ether; 1,1-[(Ethylenedioxy)bis(methylene)]-6-bromobenzene; 6-Bromoindane-1,1-diyl diethyl ether; 6-Bromo-1,1-bis(ethylenedioxy)indane (common misnomer); 6-Bromo-1,1-O,O'-ethylideneindane; 866848-94-4
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-1,1-(Ethylenedioxo)-Indane is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical-grade material typically meets a purity specification of ≥97% (by HPLC). A detailed Certificate of Analysis (COA) documenting assay, impurity profile, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.