Description

2-Bromoquinoline-4-Carboxaldehyde is a versatile and highly functionalized quinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of both a bromine atom and an aldehyde group on the quinoline scaffold, enabling sequential cross-coupling and condensation reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic libraries and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting kinases, infectious diseases, and central nervous system disorders.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by serving as a core structure for new active molecules.
• Material Science: Acts as a starting material for creating organic ligands in catalysis and for synthesizing functional organic molecules used in electronic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as a substrate for the preparation of more complex quinoline-based heterocycles.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and for exploring new reaction pathways in heterocyclic chemistry.

Basic Information

Product Name	2-Bromoquinoline-4-Carboxaldehyde
CAS No.	866831-75-6
Molecular Formula	C10H6BrNO
Molecular Weight	236.07 g/mol
Synonyms	2-Bromo-4-quinolinecarboxaldehyde; 4-Formyl-2-bromoquinoline; Quinoline-4-carboxaldehyde, 2-bromo-; 2-Bromoquinoline-4-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Bromoquinoline-4-Carboxaldehyde is manufactured and tested under a strict quality management system. We ensure high purity and consistency through comprehensive analytical techniques including HPLC, NMR, and GC-MS. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity to agreed specifications. Our quality protocols are designed to meet the stringent requirements of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.