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2-Bromo-4-Iodoquinoline CAS NO 866831-73-4
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CAS No.:866831-73-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Bromo-4-Iodoquinoline is a high-purity halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its dual halogen functionality, which enables selective cross-coupling reactions and facilitates the construction of complex heterocyclic frameworks. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of quinoline-based drug candidates targeting various therapeutic areas.
- Agrochemical Research: Used in developing novel pesticides and herbicides due to its bioactive quinoline core.
- Material Science: Serves as a monomer or functionalizing agent in the creation of organic electronic materials and metal-organic frameworks (MOFs).
- Cross-Coupling Reactions: An essential substrate for Suzuki, Stille, and Negishi couplings to introduce complex substituents.
- Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and coordination chemistry.
- Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
Basic Information
| Product Name | 2-Bromo-4-Iodoquinoline |
| CAS No. | 866831-73-4 |
| Molecular Formula | C9H5BrIN |
| Molecular Weight | 333.96 g/mol |
| Synonyms | 4-Iodo-2-bromoquinoline; Quinoline, 2-bromo-4-iodo-; 2-Bromo-4-iodoquinoline; 866831-73-4 |
| EINECS | Contact for details |
Quality Control
Our 2-Bromo-4-Iodoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines for the production of advanced pharmaceutical intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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