Description

8-Fluoro-3-Iodoquinoline is a high-value halogenated quinoline derivative, a crucial building block in advanced organic synthesis. Its unique molecular structure, featuring both fluorine and iodine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and the development of novel catalysts.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine and iodine atoms for bioactivity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport materials.
• Catalyst Ligand Development: The quinoline core can be functionalized to create novel ligands for transition metal catalysis in cross-coupling reactions.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and structure-activity relationships (SAR).
• Fluorinated Compound Library Synthesis: Essential for creating diverse libraries of fluorinated compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	8-Fluoro-3-Iodoquinoline
CAS No.	866782-59-4
Molecular Formula	C9H5F I N
Molecular Weight	273.05 g/mol
Synonyms	3-Iodo-8-fluoroquinoline; 8-Fluoro-3-iodoquinoline; Quinoline, 8-fluoro-3-iodo-; 866782-59-4; 8-Fluoro-3-iodo-quinoline
EINECS	Contact for details

Quality Control

Our 8-Fluoro-3-Iodoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.