Description

3-Bromo-4-(Bromomethyl)Benzoic Acid is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its dual reactive sites—the bromomethyl and carboxylic acid groups—which enable precise and sequential functionalization for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where its benzoic acid scaffold provides a versatile platform for structural modification.
• Liquid Crystal & OLED Material Precursor: Serves as a foundational unit for synthesizing advanced organic electronic materials, including charge-transport layers and emissive compounds.
• Polymer Modification: Employed to introduce bromine functional groups into polymer backbones, facilitating further cross-linking or grafting reactions to create specialty polymers.
• Cross-Coupling Reactions: The aryl bromide moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form biaryl structures.
• Ligand & Catalyst Development: Utilized for constructing complex chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Bromo-4-(Bromomethyl)Benzoic Acid
CAS No.	866721-92-8
Molecular Formula	C8H6Br2O2
Molecular Weight	293.94 g/mol
Synonyms	4-(Bromomethyl)-3-bromobenzoic acid; 3-Bromo-4-bromomethylbenzoic acid; Benzoic acid, 3-bromo-4-(bromomethyl)-; 2-Bromo-4-(bromomethyl)benzoic acid (numbering variant); BBA (common abbreviation); 866721-92-8; 3,4-Dibromomethylbenzoic acid (incorrect but sometimes used); 3-Bromo-4-(bromomethyl)benzenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(Bromomethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with stringent in-house specifications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring traceability, consistency, and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	155 - 160 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.