Description

(2R,4S)-2,4-Dimethylpyrrolidine Hydrochloride CAS NO 866412-04-6 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a valuable precursor for the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific stereocenters into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalyst Ligand Precursor: Used to develop and synthesize chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research laboratories.

Basic Information

Product Name	(2R,4S)-2,4-Dimethylpyrrolidine Hydrochloride
CAS No.	866412-04-6
Molecular Formula	C6H14ClN
Molecular Weight	135.64 g/mol
Synonyms	(2R,4S)-2,4-Dimethylpyrrolidine HCl; (2R,4S)-2,4-Dimethylpyrrolidinium Chloride; Pyrrolidine, 2,4-dimethyl-, hydrochloride, (2R,4S)-; (2R,4S)-2,4-Dimethylpyrrolidine Hydrochloride Salt; (2R-cis)-2,4-Dimethylpyrrolidine Hydrochloride; (2R,4S)-2,4-DMP-HCl; (2R,4S)-DMP-HCl; (2R,4S)-2,4-Dimethylpyrrolidine Monohydrochloride
EINECS	Contact for details

Quality Control

Our (2R,4S)-2,4-Dimethylpyrrolidine Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.