Description

Acetamide, N-[2-[2-(2-Aminoethoxy)ethoxy]ethyl]- is a specialized, multifunctional organic compound featuring a polyether-linked acetamide structure. This molecule is valued for its unique combination of a reactive primary amine group and a hydrophilic oligo(ethylene glycol) spacer, making it a versatile intermediate for chemical synthesis and bioconjugation. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing drug delivery systems, diagnostic agents, and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key building block for synthesizing active pharmaceutical ingredients (APIs), particularly for drugs requiring pegylated or hydrophilic modifications.
• Bioconjugation Linker: Used to attach drugs, dyes, or other functional molecules to proteins, antibodies, or nanoparticles via its amine-reactive group and biocompatible PEG chain.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating smart hydrogels, non-fouling surfaces, and stimuli-responsive materials.
• Diagnostic Reagent Synthesis: Employed in the production of contrast agents and fluorescent probes for medical imaging and bioassays.
• Surface Functionalization: Used to introduce amine-terminated, hydrophilic layers onto various substrates (e.g., glass, gold, polymers) for biosensor and microarray applications.
• Research & Development: A valuable tool compound in organic and medicinal chemistry research for exploring new synthetic pathways and bio-active molecules.

Basic Information

Product Name	Acetamide, N-[2-[2-(2-Aminoethoxy)ethoxy]ethyl]-
CAS No.	866404-69-5
Molecular Formula	C10H22N2O4
Molecular Weight	234.29 g/mol
Synonyms	2,2'-(2-(2-Aminoethoxy)ethoxy)di(ethylamine) monoacetamide; N1-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)acetamide; 11-Amino-3,6,9-trioxaundecan-1-amine monoacetamide; Acetamide-PEG3-amine; Amino-PEG3-acetamide; Amine-PEG3-acetamide; Ac-PEG3-NH2; N-(8-Amino-3,6-dioxaoctyl)acetamide
EINECS	Contact for details

Quality Control

Our Acetamide, N-[2-[2-(2-Aminoethoxy)ethoxy]ethyl]- is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Primary Amine Assay (Titration)	≥ 90.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.