Description

3,3-Dimethyl-5-Fluorooxindole is a high-purity fluorinated oxindole derivative, a crucial advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in its unique molecular scaffold, which is integral to the development of novel bioactive compounds, particularly in medicinal chemistry. This product is essential for research and development scientists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate a fluorinated heterocyclic moiety into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology drug candidates.
• Medicinal Chemistry Research: Serves as a privileged scaffold for designing and synthesizing new chemical entities (NCEs) for biological screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the oxindole core.
• Fine Chemical Building Block: Employed in multi-step organic synthesis to construct complex molecules for material science and specialty chemical applications.
• Fluorination Chemistry Studies: Acts as a model compound for investigating the effects of fluorine substitution on the physicochemical properties and metabolic stability of heterocyclic compounds.

Basic Information

Product Name	3,3-Dimethyl-5-Fluorooxindole
CAS No.	866209-99-6
Molecular Formula	C10H10FNO2
Molecular Weight	195.19 g/mol
Synonyms	5-Fluoro-3,3-dimethyl-1,3-dihydro-2H-indol-2-one; 5-Fluoro-3,3-dimethylindolin-2-one; 3,3-Dimethyl-5-fluoro-2-indolinone; 5-Fluoro-3,3-dimethyloxindole; 866209-99-6; 3,3-Dimethyl-5-fluoro-1,3-dihydro-2H-indol-2-one
EINECS	Contact for details

Quality Control

Our 3,3-Dimethyl-5-Fluorooxindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.