Description

2-Phenethyl-1-(Trifluoromethyl)-5,6-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinoline is a high-value, complex heterocyclic compound featuring a fused pyrroloquinoline core with a phenethyl and a trifluoromethyl substituent. This molecular architecture makes it a critical advanced intermediate or building block in modern synthetic chemistry, particularly for developing novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by pharmaceutical R&D, agrochemical research, and specialty chemical synthesis teams requiring sophisticated scaffolds for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the quinoline and trifluoromethyl motifs.
• Material Science Precursor: Acts as an intermediate for creating organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Fluorinated Compound Synthesis: The trifluoromethyl group makes it a valuable synthon for introducing fluorine into target molecules to enhance metabolic stability and lipophilicity.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	2-Phenethyl-1-(Trifluoromethyl)-5,6-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinoline
CAS No.	866049-84-5
Molecular Formula	C22H20F3N
Molecular Weight	355.40 g/mol
Synonyms	1-(Trifluoromethyl)-2-phenethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline; 2-Phenethyl-1-(trifluoromethyl)-4H,5H,6H-pyrrolo[3,2,1-ij]quinoline; 866049-84-5; Pyrrolo[3,2,1-ij]quinoline, 5,6-dihydro-2-(2-phenylethyl)-1-(trifluoromethyl)-; 2-(2-Phenylethyl)-1-(trifluoromethyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline
EINECS	Contact for details

Quality Control

Our production of 2-Phenethyl-1-(Trifluoromethyl)-5,6-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinoline adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our facilities operate under cGMP-compliant principles where applicable, ensuring traceability and reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.