Description

(Z)-2-(1,3-Benzodioxol-5-Yl)-3-(1-Isobutyl-1,2,3,4-Tetrahydro-6-Quinolinyl)-2-Propenenitrile is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Fine Chemical Synthesis: Serves as a precursor for the manufacture of complex, high-value specialty chemicals.
• Biochemical Research: Potential tool compound for investigating biological pathways and receptor interactions in academic and industrial settings.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	(Z)-2-(1,3-Benzodioxol-5-Yl)-3-(1-Isobutyl-1,2,3,4-Tetrahydro-6-Quinolinyl)-2-Propenenitrile
CAS No.	866039-70-5
Molecular Formula	C23H24N2O2
Molecular Weight	360.45 g/mol
Synonyms	(Z)-2-(1,3-Benzodioxol-5-yl)-3-(1-isobutyl-1,2,3,4-tetrahydroquinolin-6-yl)acrylonitrile; 2-(1,3-Benzodioxol-5-yl)-3-(1-isobutyl-1,2,3,4-tetrahydro-6-quinolyl)-2-propenenitrile (Z)-; 6-[(1Z)-2-Cyano-2-(1,3-benzodioxol-5-yl)ethenyl]-1-isobutyl-1,2,3,4-tetrahydroquinoline; Z-Isomer of the named acrylonitrile derivative; 1-Isobutyl-6-[(Z)-2-(1,3-benzodioxol-5-yl)-1-cyanoethenyl]-1,2,3,4-tetrahydroquinoline; Contact for additional trade names and identifiers.
EINECS	Contact for details

Quality Control

Our (Z)-2-(1,3-Benzodioxol-5-Yl)-3-(1-Isobutyl-1,2,3,4-Tetrahydro-6-Quinolinyl)-2-Propenenitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and consistency for your critical R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); it is recommended to store under an inert gas (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0% (Area %)
Z-Isomer Content (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.