Description

4H-Cyclopenta-1,3-Dioxol-4-Ol, 3A,6A-Dihydro-2,2-Dimethyl-4-[(Triphenylmethoxy)Methyl]-, (3As,4R,6As)- is a sophisticated chiral intermediate of significant importance in advanced organic synthesis. Its core value lies in its unique stereochemistry and functional groups, which make it a critical building block for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and fine chemical industries, where it serves as a key precursor for active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Nucleoside/Nucleotide Chemistry: Used in the preparation of modified nucleosides and nucleotides for antiviral or anticancer drug discovery programs.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to introduce specific stereocenters.
• Protecting Group Strategy: The triphenylmethoxy (trityl) group is a valuable protecting group for alcohols in complex synthetic routes.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable manufacturing processes for target molecules.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	4H-Cyclopenta-1,3-Dioxol-4-Ol, 3A,6A-Dihydro-2,2-Dimethyl-4-[(Triphenylmethoxy)Methyl]-, (3As,4R,6As)-
CAS No.	865838-13-7
Molecular Formula	C26H26O4
Molecular Weight	402.48 g/mol
Synonyms	(3aS,4R,6aS)-3a,6a-Dihydro-2,2-dimethyl-4-[(triphenylmethoxy)methyl]-4H-cyclopenta-1,3-dioxol-4-ol; (4R)-4-[(Trityloxy)methyl]-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol acetonide; 4-[(Triphenylmethoxy)methyl]-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol cyclic acetonide (stereospecific); Trityl-protected isopropylidene derivative of a pentose derivative; Chiral dioxolane-trityl ether intermediate.
EINECS	Contact for details

Quality Control

Our 4H-Cyclopenta-1,3-Dioxol-4-Ol derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.