Description

(S)-1-[2-(Trifluoromethyl)Phenyl]Ethylamine-Hcl CAS NO 865815-09-4 is a high-purity chiral amine hydrochloride salt, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a defined stereocenter essential for creating enantiomerically pure compounds with targeted biological activity. This intermediate is primarily needed by research and development laboratories, process chemists, and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Building block for developing enantiomerically pure herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Preparation: Used in the synthesis of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate for specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic and R&D: Valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Process Chemistry: Scalable intermediate for optimizing synthetic routes toward commercial targets in kilo-lab and pilot plant settings.

Basic Information

Product Name	(S)-1-[2-(Trifluoromethyl)Phenyl]Ethylamine Hydrochloride
CAS No.	865815-09-4
Molecular Formula	C9H10F3N•HCl
Molecular Weight	225.64 g/mol
Synonyms	(S)-1-[2-(Trifluoromethyl)phenyl]ethanamine hydrochloride; (S)-α-Methyl-2-(trifluoromethyl)benzylamine hydrochloride; (S)-1-(2-Trifluoromethylphenyl)ethylamine HCl; (S)-2-(Trifluoromethyl)phenethylamine hydrochloride; (S)-1-(2-Trifluoromethylphenyl)ethan-1-amine hydrochloride; (S)-TFMPEA HCl; (S)-1-(2-CF3-C6H4)-C2H5-NH2•HCl
EINECS	Contact for details

Quality Control

Our (S)-1-[2-(Trifluoromethyl)Phenyl]Ethylamine-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), residual solvents, and other critical parameters is provided with every shipment to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert conditions after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.